An example of four genomes with a phylogenetic tree and their multiple breakpoint graph. (a) A phylogenetic tree with four circular genomes P1, P2, P3, P4 (represented as green, blue, red, and yellow graphs respectively) at the leaves and specified intermediate genomes. The obverse edges are not shown. (b) The multiple breakpoint graph G(P1, P2, P3, P4) is a superposition of graphs representing genomes P1, P2, P3, P4.
Alekseyev and Pevzner Genome Biology 2010 11:R117 doi:10.1186/gb-2010-11-11-r117