Constructing a fish metabolic network model
1 Gulf Coast Research Laboratory, Department of Coastal Sciences, University of Southern Mississippi, 703 East Beach Drive, Ocean Springs, MS 39564, USA
2 Current address: Emory Vaccine Center, 954 Gatewood Rd, Atlanta, GA 30329, USA
3 Current address: Max Planck Institute, August-Thienemann-Str. 2, Ploen 24306, Germany
Genome Biology 2010, 11:R115 doi:10.1186/gb-2010-11-11-r115Published: 29 November 2010
We report the construction of a genome-wide fish metabolic network model, MetaFishNet, and its application to analyzing high throughput gene expression data. This model is a stepping stone to broader applications of fish systems biology, for example by guiding study design through comparison with human metabolism and the integration of multiple data types. MetaFishNet resources, including a pathway enrichment analysis tool, are accessible at http://metafishnet.appspot.com webcite.