Receiver-operator characteristic and positive predictive power versus negative predictive power plots for lung cancer data. (a) Sensitivity versus '1 - specificity' of enriched pathways that are predictive of survival from lung cancer for four methods: SEPEA_NT1, SEPEA_NT1*, GSEA and maxmean. SEPEA_NT1* is the same analysis as SEPEA_NT1 except that the pathway network information was not used. (b) Positive predictive power (ppp) versus negative predictive power (npp) for the same data and using the same methods of analysis as in (a).
Thomas et al. Genome Biology 2009 10:R44 doi:10.1186/gb-2009-10-4-r44