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The FANTOM web resource: from mammalian transcriptional landscape to its dynamic regulation

Hideya Kawaji1*, Jessica Severin1, Marina Lizio1, Andrew Waterhouse1, Shintaro Katayama1, Katharine M Irvine2, David A Hume3, Alistair RR Forrest14, Harukazu Suzuki1, Piero Carninci1, Yoshihide Hayashizaki1 and Carsten O Daub1

Author Affiliations

1 RIKEN Omics Science Center, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho Tsurumi-ku Yokohama, Kanagawa, 230-0045 Japan

2 Institute for Molecular Bioscience, University of Queensland, Brisbane, St Lucia QLD 4072, Australia

3 The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Roslin, EH259PS, UK

4 The Eskitis Institute for Cell and Molecular Therapies, Griffith University, QLD 4111, Australia

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Genome Biology 2009, 10:R40  doi:10.1186/gb-2009-10-4-r40

Published: 19 April 2009


In FANTOM4, an international collaborative research project, we collected a wide range of genome-scale data, including 24 million mRNA 5'-reads (CAGE tags) and microarray expression profiles along a differentiation time course of the human THP-1 cell line and under 52 systematic siRNA perturbations. In addition, data regarding chromatin status derived from ChIP-chip to elucidate the transcriptional regulatory interactions are included. Here we present these data to the research community as an integrated web resource.