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COMIT: identification of noncoding motifs under selection in coding sequences

Deniz Kural, Yang Ding, Jiantao Wu, Alicia M Korpi and Jeffrey H Chuang*

Author Affiliations

Department of Biology, Boston College, 140 Commonwealth Avenue, Chestnut Hill, MA 02467, USA

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Genome Biology 2009, 10:R133  doi:10.1186/gb-2009-10-11-r133

Published: 20 November 2009

Additional files

Additional data file 1:

Figure S1: improved correlation in z-score and Ks for larger clades. Figure S2: comparison of naïve codon completion and nucleotide-by-nucleotide Ks methods. Figure S3: comparison of mouse-human COMIT scores to scores uncalibrated for amino acids.

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Additional data file 2:

COMIT scores and nucleotide-by-nucleotide Ks values for hexamers. Table S1: COMIT scores for all hexamers in multiple lineage comparisons. Table S2: Ks values. Table S3: motifs with z > 15 in all three mammalian lineages.

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