Hierarchical clustering of animals in the high dose/48 hour group using SVM-derived classifiers. Two-way hierarchical clustering using Ward's minimum variance as the heuristic criteria and Euclidean distance as the similarity metric was performed on all of the animals in the high dose/48 hour group using the blood expression values for the 60 transcripts identified as compound classifiers for this dose/time group by a SVM algorithm. The degree of relatedness between each sample is represented by the dendrogram (hierarchical tree) presented in this figure, wherein the height of each branch represents the distance between the two objects being connected.
Lobenhofer et al. Genome Biology 2008 9:R100 doi:10.1186/gb-2008-9-6-r100