Within the core genome the DUS proximal regions accumulate more substitutions. The black line represents the percent identity for regions surrounding all exactly conserved DNA uptake sequence (DUS) in the multiple alignments. The red line corresponds to the percentage identity for regions surrounding randomly selected DUS-less sites in the multiple alignment. (a) All DUSs analyzed. (b) Only DUSs contained inside protein coding sequences.
Treangen et al. Genome Biology 2008 9:R60 doi:10.1186/gb-2008-9-3-r60