Schematic diagram of the domain structures of the orphan myosins of species not belonging to one of the other taxa. Both alleles of Trypanosoma cruzi have been assembled independently, providing two slightly different copies of each myosin gene. None of the Myo-F versions is complete and the presented domain organization of Myo-F is the result of a merged version of both myosins. The sequence names of the ophan myosins are given in the motor domain of the respective myosins. Color keys to the domain names and symbols are given on the right except for the myosin domain, which is colored in blue. Myosin names next to domain representations list orthologs from closely related species or orthologs from the same species. These sequences have a similar domain organization. Sequences that are not orthologs and have not resulted from recent gene duplications are shown separately, although their domain organizations might be very similar. Abbreviations for the domains are: AAA, ATPase family associated with various cellular activities; DnaJ domain, named after the prokaryotic heat shock protein DnaJ; RhoGEF, Rho GDP/GTP exchange factor.
Odronitz and Kollmar Genome Biology 2007 8:R196 doi:10.1186/gb-2007-8-9-r196