Additional data file 1.
Figure S1 shows motif coverage of protein sequences compared with coverage of the protein-protein interaction binding sites. Figure S2 is an illustration of the Bayesian network used in the first phase of InSite. Figure S3 is a schematic illustration of our EM-based learning algorithm. Figure S4 is an illustration of the Bayesian network used in the second phase of InSite. Figure S5 shows the number of motifs and their lengths on each protein. Figure S6 shows the number of occurrences for each pair of motif types. Figure S7 evaluates motif-protein binding site predictions with or without indirect evidence relative to solved PDB structures. Figure S8 shows the statistics for each protein-protein interaction dataset.
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Wang et al. Genome Biology 2007 8:R192 doi:10.1186/gb-2007-8-9-r192