Additional data file 8.

Heatmap of gene expression of the 11-gene humoral IR module in the ER+ samples of the (A) UPP and (B) JRH-2 cohorts. Shown are the clusters over-expressing (purple) and underexpressing (yellow) the humoral IR module as predicted by the pam algorithm. Good outcome samples are presented in gray and poor outcome samples in black. Green indicates relative under-expression, and red relative over-expression. (C) Kaplan-Meier survival curves over combined external cohorts (for UPP the end-point was disease-specific survival, and for JRH-2 it was recurrence-free survival), with the number of events and samples in each of the two predicted groups.

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Teschendorff et al. Genome Biology 2007 8:R157   doi:10.1186/gb-2007-8-8-r157