Overlap of differentially expressed functional categories in long-lived nematodes, fruitflies and mice. These Venn diagrams show the number and overlap of significantly differentially regulated functional categories (p < 0.05; GO categories and Interpro domain families) identified in each dataset using Catmap. While most of the differentially expressed categories in each dataset are species-specific, a small number of categories (boxed) show significant changes in expression in response to reduced IIS in all three species. These categories are detailed in Table 5.
McElwee et al. Genome Biology 2007 8:R132 doi:10.1186/gb-2007-8-7-r132