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Open Access Research

Modular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages

Antonio del Sol1*, Marcos J Araúzo-Bravo1, Dolors Amoros1 and Ruth Nussinov23

Author Affiliations

1 Bioinformatics Research Unit, Research and Development Division, Fujirebio Inc., Komiya-cho, Hachioji-shi, Tokyo 192-0031, Japan

2 Basic Research Program, SAIC-Frederick, Inc., Center for Cancer Research, Nanobiology Program, National Cancer Institute, Frederick, MD 21702, USA

3 Sackler Institute of Molecular Medicine, Department of Human Genetics and Molecular Medicine, Tel Aviv University, Tel Aviv 69978, Israel

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Genome Biology 2007, 8:R92  doi:10.1186/gb-2007-8-5-r92

Published: 25 May 2007

Additional files

Additional data file 1:

Additional examples of protein modularity and the datasets used for the analyses.

Format: DOC Size: 1.7MB Download file

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Open Data