Histone H4 lysine 16 acetylation breaks the genome's silence
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Genome Biology 2006, 7:217 doi:10.1186/gb-2006-7-5-217Published: 10 May 2006
Acetylation at histone H4 lysine 16 is involved in many cellular processes in organisms as diverse as yeast and humans. A recent biochemical study pinpoints this particular acetylation mark as a switch for changing chromatin from a repressive to a transcriptionally active state.