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The dynamic proteome of Lyme disease Borrelia

Steven J Norris

Author Affiliations

Departments of Pathology and Laboratory Medicine and Microbiology and Molecular Genetics, University of Texas Medical School, Houston, TX 77225-0708, USA

Genome Biology 2006, 7:209  doi:10.1186/gb-2006-7-3-209

Published: 17 March 2006


The proteome of the spirochete bacterium Borrelia burgdorferi, the tick-borne agent of Lyme disease, has been characterized by two different approaches using mass spectrometry, providing a launching point for future studies on the dramatic changes in protein expression that occur during transmission of the bacterium between ticks and mammals.