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Distinct yet linked: chaperone networks in the eukaryotic cytosol

Sabine Rospert* and Agnieszka Chacinska

Author Affiliations

Institute of Biochemistry and Molecular Biology, University of Freiburg, Hermann-Herder-Strasse 7, D-79104 Freiburg, Germany.

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Genome Biology 2006, 7:208  doi:10.1186/gb-2006-7-3-208

Published: 31 March 2006


The terms chaperone and heat-shock protein are frequently used as synonyms, but this is an oversimplification. Although one subset of chaperones is induced by heat stress, a distinct group fails to respond in the same manner. Recent work reveals that this latter group is linked to the translational apparatus and functions in co-translational processes.