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Genetic control of hippocampal neurogenesis

Christine D Pozniak and Samuel J Pleasure*

Author Affiliations

Department of Neurology, Programs in Neuroscience and Developmental Biology, University of California, San Francisco, CA 94143, USA.

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Genome Biology 2006, 7:207  doi:10.1186/gb-2006-7-3-207

Published: 30 March 2006


Adult neurogenesis in the hippocampus is under complex genetic control. A recent comparative study of two inbred mouse strains using quantitative trait locus analysis has revealed that cell survival is most highly correlated with neurogenesis and identified candidate genes for further investigation.