Resolution:
## Figure 1.
ExportPred: Architecture and performance.
(a) The architecture of the ExportPred GHMM. The GHMM progresses from left to right, beginning
with an amino-terminal methionine and terminating at a stop codon. Length probability
densities are shown for non-geometric states. Tail states and the KLD spacer state
are modelled by geometric distributions. (b) ROC curves for the ExportPred model comparing the training against the five described
negative sets. (c) False discovery rate as a function of score threshold, calculated using the training
set and the P.f negative set, and assuming 10% of the P. falciparum proteome is exported. (d) Comparison of predictions made by ExportPred using the default threshold of 4.3 with
those published in [6,7]. The -rifin set is exclusive of any sequence annotated as
rifin or stevor, whereas the +rifin set includes these sequences.
Sargeant |