Schema for core histone gene promoters. (a) Four different human core histone gene promoters are shown along with the relative locations of predicted cis-binding motifs. Official gene names are indicated for each promoter. These are examples of genes that are not divergently transcribed because a pair of divergently transcribed genes share identical motifs. (b) Yeast (S. cerevisiae) bidirectional core histone promoters and cis-binding motifs. The promoter sequences and, accordingly, the location/presence of the cis-motifs of individual members of each family may vary for each gene. Not drawn to scale.
Mariño-Ramírez et al. Genome Biology 2006 7:R122 doi:10.1186/gb-2006-7-12-r122