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Where is the difference between the genomes of humans and annelids?

Alexei Fedorov12* and Larisa Fedorova1

Author Affiliations

1 Department of Medicine, Medical University of Ohio, Toledo, OH 43614, USA

2 Program in Bioinformatics and Proteomics/Genomics, Medical University of Ohio, Toledo, OH 43614, USA

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Genome Biology 2006, 7:203  doi:10.1186/gb-2006-7-1-203

Published: 1 February 2006


The first systematic investigation of an annelid genome has revealed that the genes of the marine worm Platynereis dumerilii are more closely related to those of vertebrates than to those of insects or nematodes. For hundreds of millions of years vertebrates have preserved exon-intron structures descended from their last common ancestor with the annelids.