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Validation and refinement of gene-regulatory pathways on a network of physical interactions

Chen-Hsiang Yeang1, H Craig Mak2, Scott McCuine2, Christopher Workman2, Tommi Jaakkola3 and Trey Ideker2*

Author Affiliations

1 Center for Biomolecular Science and Engineering, Baskin School of Engineering, University of California at Santa Cruz, Santa Cruz, CA 95064, USA

2 Department of Bioengineering, University of California at San Diego, La Jolla, CA 92093, USA

3 Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA

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Genome Biology 2005, 6:R62  doi:10.1186/gb-2005-6-7-r62

Published: 1 July 2005

Additional files

Additional File 1:

Table S1 gives the internal validation for 17 out of 24 restricted network models; Table S2 lists the correlations between swi4δ and gcn4δ data and Rosetta and the new experiments; Table S3 gives the restricted subsets used to evaluate the reproducibility; and Table S4 gives the gene sets for external validation.

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