Email updates

Keep up to date with the latest news and content from Genome Biology and BioMed Central.

Open Badges Opinion

Flexible peptides and cytoplasmic gels

Dennis Bray

Author Affiliations

Department of Anatomy, University of Cambridge, Cambridge CB2 3DY, UK

Genome Biology 2005, 6:106  doi:10.1186/gb-2005-6-3-106

Published: 28 February 2005


Recent progress in predicting protein structures has revealed a surprising abundance of proteins that are significantly unfolded under physiological conditions. Unstructured, flexible polypeptides are likely to be functionally important and may cause local cytoplasmic regions to become gel-like.