Flexible peptides and cytoplasmic gels
Department of Anatomy, University of Cambridge, Cambridge CB2 3DY, UK
Genome Biology 2005, 6:106 doi:10.1186/gb-2005-6-3-106Published: 28 February 2005
Recent progress in predicting protein structures has revealed a surprising abundance of proteins that are significantly unfolded under physiological conditions. Unstructured, flexible polypeptides are likely to be functionally important and may cause local cytoplasmic regions to become gel-like.