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Enriching for direct regulatory targets in perturbed gene-expression profiles

Susannah G Tringe13, Andreas Wagner2 and Stephanie W Ruby1*

Author Affiliations

1 Department of Molecular Genetics and Microbiology, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA

2 Department of Biology, University of New Mexico, Albuquerque, NM 87131, USA

3 Current address: DOE Joint Genome Institute, 2800 Mitchell Drive, Bldg 400, Walnut Creek, CA 94596, USA

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Genome Biology 2004, 5:R29  doi:

Published: 30 March 2004

Additional files

Additional data file 1:

A PDF file containing four appendices including a detailed discussion of the parameters of the synthetic networks used in simulations, the transcription factors and targets identified as described in the main text, the Perl code for the algorithm described in the paper and a sample text input file for the algorithm

Format: PDF Size: 185KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data