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Prediction for Target Sites of Small Interfering RNA Duplexes in SARS Coronavirus
1 Institute for Biological Science and Technology,Faculty of Sciences, North Jiaotong University, Beijing, 100044 China
2 Laboratory of Theoretical Biophysics, Faculty of Sciences and Technology, Inner Mongolia University, Hohhot, 010021 China
3 Center for Theoretical Biology, Peking University, Beijing, 100871 China
Genome Biology 2004, 5:P6 doi:10.1186/gb-2004-5-2-p6
This is the first version of this article to be made available publicly.Published: 16 January 2004
RNA interference is used for SARS-related pharmaceutical research and development. Following bioinformatic method twenty seven 21~25 base-long sequence segments in SARS-CoV genome are predicted as the optimal target sites of small interfering RNA duplexes.