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The genomics and proteomics of biofilm formation

Karin Sauer

Author Affiliations

State University of New York at Binghamton, 104 Science III, Vestal Parkway East, Binghamton, NY 13902, USA

Genome Biology 2003, 4:219  doi:10.1186/gb-2003-4-6-219

Published: 27 May 2003


Bacterial communities that are attached to a surface, so-called biofilms, and their inherent resistance to antimicrobial agents are a cause of many persistent and chronic bacterial infections. Recent genomic and proteomic studies have identified many of the genes and gene products differentially expressed during biofilm formation, revealing the complexity of this developmental process.