Multi-VISTA display of a 5 kilobase fragment of the MLAGAN alignment of the CFTR region . This view is based on the coordinates of the human sequence and displays the level of conservation between human and all other sequences in the multiple alignment. A fragment of the CAV1 gene is shown as an arrow above the plots. The following cutoffs were used to show the conserved regions: above 80% over 100 bp for chimpanzee, baboon, cat, dog, cow, pig, mouse and rat; above 65% over 100 bp for chicken; above 50% over 100 bp for Fugu and zebrafish.
Dubchak and Frazer Genome Biology 2003 4:122 doi:10.1186/gb-2003-4-12-122