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Error-prone polymerases make efficient immunity

Tudor Toma

Genome Biology 2001, 2:spotlight-20010601-01  doi:10.1186/gb-spotlight-20010601-01

Published: 1 June 2001

Multiple error-prone DNA polymerases contribute to immunoglobulin somatic hypermutation - the process behind increasing antibody affinities after multiple exposures to the same antigen.