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A conserved mechanism for post-transcriptional gene silencing?

Eleanor M Maine

Author Affiliations

Department of Biology, Syracuse University, Syracuse, NY 13244, USA

Genome Biology 2000, 1:reviews1018-reviews1018.4  doi:10.1186/gb-2000-1-3-reviews1018

Published: 13 September 2000


Proteins with homology to RNA-directed RNA polymerases function in post-transcriptional gene silencing: in quelling in the fungus Neurospora crassa, RNAi in the nematode Caenorhabditis elegans, and co-suppression in the mustard plant Arabidopsis thaliana. These findings are consistent with a conserved mechanism operating in these diverse species.