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Gadd45a knockout mice resemble p53 knockouts

Jonathan B Weitzman

Genome Biology 2000, 1:reports002  doi:10.1186/gb-2000-1-1-reports002

Published: 17 March 2000


Mice with a disrupted Gadd45a gene share several phenotypic characteristics with p53 knockout mice, including genomic instability, increased carcinogenesis and exencephaly.