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Yersinia perturbs host cell signaling

Jonathan B Weitzman

Genome Biology 2000, 1:reports001  doi:10.1186/gb-2000-1-1-reports001

Published: 17 March 2000


YopJ, a virulence factor of Yersinia pseudotuberculosis, can bind to several key intracellular signaling proteins, members of the MAPKK family, preventing their activation and protecting the pathogen from host defense mechanisms.